Version 5.4
Homo sapiens Gene: SLC12A7
Summary
InnateDB Gene IDBG-10791.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC12A7
Gene Name solute carrier family 12 (potassium/chloride transporters), member 7
Synonyms KCC4
Species Homo sapiens
Ensembl Gene ENSG00000113504
Encoded Proteins
IDBP-10793
solute carrier family 12 (potassium/chloride transporters), member 7
IDBP-480724
solute carrier family 12 (potassium/chloride transporters), member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:1050376-1112035
Strand Reverse strand
Band p15.33
Transcripts
ENST00000264930 ENSP00000264930
ENST00000514994
ENST00000513223 ENSP00000428854
ENST00000504576
ENST00000510943
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015377 cation:chloride symporter activity
GO:0015379 potassium:chloride symporter activity
GO:0019901 protein kinase binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0006821 chloride transport
GO:0006884 cell volume homeostasis
GO:0055085 transmembrane transport
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000017756
View Gene Order
ENSBTAG00000006775
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_19315
Cation-coupled Chloride cotransporters pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
hsa04966
Collecting duct acid secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.172613
RefSeq NM_006598
HUGO
OMIM
CCDS CCDS34129
HPRD 09221
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca