Version 5.4
Homo sapiens Gene: TAPT1
Summary
InnateDB Gene IDBG-10813.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAPT1
Gene Name transmembrane anterior posterior transformation 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000169762
Encoded Proteins
IDBP-292818
transmembrane anterior posterior transformation 1
IDBP-474898
transmembrane anterior posterior transformation 1
IDBP-481440
transmembrane anterior posterior transformation 1
IDBP-478505
transmembrane anterior posterior transformation 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a highly conserved, putative transmembrane protein. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. This gene is proposed to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. An alternatively spliced transcript variant encoding a substantially different isoform has been described, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:16160505-16227410
Strand Reverse strand
Band p15.32
Transcripts
ENST00000405303 ENSP00000385347
ENST00000503858
ENST00000505603 ENSP00000422652
ENST00000513782 ENSP00000423359
ENST00000508886
ENST00000507728
ENST00000488714
ENST00000507425
ENST00000504281
ENST00000513359
ENST00000508888
ENST00000510868
ENST00000505152
ENST00000511866
ENST00000513833 ENSP00000422752
ENST00000505317
ENST00000511156
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016520 growth hormone-releasing hormone receptor activity
Biological Process
GO:0001701 in utero embryonic development
GO:0007186 G-protein coupled receptor signaling pathway
GO:0009791 post-embryonic development
GO:0048706 embryonic skeletal system development
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000046985
View Gene Order
ENSBTAG00000019451
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.479223 Hs.696543
RefSeq NM_153365 XM_005248139 XM_005248140 XM_005248141 XM_005248142
HUGO
OMIM
CCDS CCDS47030
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca