Version 5.4
Homo sapiens Protein: TAPT1
Summary
InnateDB Protein IDBP-292818.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAPT1
Protein Name transmembrane anterior posterior transformation 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000385347
InnateDB Gene IDBG-10813 (TAPT1)
Protein Structure
UniProt Annotation
Function May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). In case of infection, may act as a fusion receptor for cytomegalovirus (HCMV) strain AD169. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016520 growth hormone-releasing hormone receptor activity
Biological Process
GO:0001701 in utero embryonic development
GO:0007186 G-protein coupled receptor signaling pathway
GO:0009791 post-embryonic development
GO:0048706 embryonic skeletal system development
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR008010 Membrane protein,Tapt1/CMV receptor
PFAM PF05346
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NXT6
PhosphoSite PhosphoSite-Q6NXT6
TrEMBL B4DJJ3
UniProt Splice Variant
Entrez Gene 202018
UniGene Hs.696543
RefSeq NP_699196
HUGO HGNC:26887
OMIM 612758
CCDS CCDS47030
HPRD
IMGT
EMBL AC108063 AC110088 AF189251 AK074494 AK296104 BC066899 CH471069
GenPept AAF28308 AAH66899 BAC11022 BAG58855 EAW92754

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca