Version 5.4
Homo sapiens Gene: SAMM50
Summary
InnateDB Gene IDBG-10862.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SAMM50
Gene Name sorting and assembly machinery component 50 homolog (S. cerevisiae)
Synonyms OMP85; SAM50; TOB55; TRG-3; YNL026W
Species Homo sapiens
Ensembl Gene ENSG00000100347
Encoded Proteins
IDBP-10864
sorting and assembly machinery component 50 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The Sam complex functions in the assembly of beta-barrel proteins into the outer mitochondrial membrane.[provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:43955421-44010531
Strand Forward strand
Band q13.31
Transcripts
ENST00000350028 ENSP00000345445
ENST00000493161
ENST00000474323
ENST00000494795
ENST00000465768
ENST00000493621
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 30 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006626 protein targeting to mitochondrion
GO:0044267 cellular protein metabolic process
GO:0045040 protein import into mitochondrial outer membrane
Cellular Component
GO:0001401 mitochondrial sorting and assembly machinery complex
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
GO:0019867 outer membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022437
View Gene Order
ENSBTAG00000045957
Not yet available
Pathways
NETPATH
REACTOME
REACT_118595
Mitochondrial protein import pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9Y512
TrEMBL A8MZI2
UniProt Splice Variant
Entrez Gene 25813
UniGene Hs.737716
RefSeq NM_015380
HUGO HGNC:24276
OMIM 612058
CCDS CCDS14055
HPRD 10826
IMGT
EMBL AF151809 AK001087 AK222657 AL035398 AY189688 BC007830 BC011681 BC015200 CH471138 CR456483
GenPept AAD34046 AAH07830 AAH11681 AAH15200 AAO85221 BAA91498 BAD96377 CAB51401 CAG30369 EAW73326
RNA Seq Atlas 25813

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca