InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SAMM50

Summary

InnateDB Protein

IDBP-10864.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SAMM50

Protein Name

sorting and assembly machinery component 50 homolog (S. cerevisiae)

Synonyms

OMP85; SAM50; TOB55; TRG-3; YNL026W;

Species

Homo sapiens

Ensembl Protein

ENSP00000345445

InnateDB Gene

IDBG-10862 (SAMM50)

Protein Structure

UniProt Annotation

Function

May be required for the assembly pathway of mitochondrial outer membrane proteins. {ECO:0000250}.

Subcellular Localization

Mitochondrion outer membrane {ECO:0000269PubMed:12601808}; Multi-pass membrane protein {ECO:0000269PubMed:12601808}. Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006626	protein targeting to mitochondrion
GO:0044267	cellular protein metabolic process
GO:0045040	protein import into mitochondrial outer membrane

Cellular Component

GO:0001401	mitochondrial sorting and assembly machinery complex
GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0005743	mitochondrial inner membrane
GO:0016021	integral component of membrane
GO:0019867	outer membrane
GO:0070062	extracellular vesicular exosome