Version 5.4
Homo sapiens Gene: SHC4
Summary
InnateDB Gene IDBG-11293.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SHC4
Gene Name SHC (Src homology 2 domain containing) family, member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185634
Encoded Proteins
IDBP-11295
SHC (Src homology 2 domain containing) family, member 4
IDBP-237304
SHC (Src homology 2 domain containing) family, member 4
IDBP-588617
SHC (Src homology 2 domain containing) family, member 4
IDBP-591279
SHC (Src homology 2 domain containing) family, member 4
IDBP-601083
SHC (Src homology 2 domain containing) family, member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:48823735-48963444
Strand Reverse strand
Band q21.1
Transcripts
ENST00000332408 ENSP00000329668
ENST00000396535 ENSP00000379786
ENST00000537958 ENSP00000443300
ENST00000557797 ENSP00000453344
ENST00000558220 ENSP00000453397
ENST00000559289
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0030971 receptor tyrosine kinase binding
Biological Process
GO:0006915 apoptotic process
GO:0008284 positive regulation of cell proliferation
GO:0010468 regulation of gene expression
GO:0035556 intracellular signal transduction
GO:0048863 stem cell differentiation
Cellular Component
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035109
View Gene Order
ENSBTAG00000022583
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04012
ErbB signaling pathway pathway
hsa05214
Glioma pathway
hsa04910
Insulin signaling pathway pathway
hsa04510
Focal adhesion pathway
hsa04650
Natural killer cell mediated cytotoxicity pathway
hsa05220
Chronic myeloid leukemia pathway
hsa04722
Neurotrophin signaling pathway pathway
hsa04062
Chemokine signaling pathway pathway
hsa05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL B3KWE9 F5H5M1 H0YLZ2
UniProt Splice Variant
Entrez Gene 399694
UniGene Hs.585204 Hs.599568 Hs.642615
RefSeq NM_203349 XM_005254375 XM_006720503
HUGO HGNC:16743
OMIM
CCDS CCDS10130
HPRD 15289
IMGT
EMBL AC012379 AC091073 AK124916
GenPept BAG54111
RNA Seq Atlas 399694

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca