Version 5.4
Homo sapiens Gene: PAPD7
Summary
InnateDB Gene IDBG-11696.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PAPD7
Gene Name PAP associated domain containing 7
Synonyms LAK-1; LAK1; POLK; POLS; TRF4; TRF4-1; TRF41; TUTASE5
Species Homo sapiens
Ensembl Gene ENSG00000112941
Encoded Proteins
IDBP-11698
PAP associated domain containing 7
IDBP-477569
PAP associated domain containing 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:6714605-6757048
Strand Forward strand
Band p15.31
Transcripts
ENST00000230859 ENSP00000230859
ENST00000515721 ENSP00000427232
ENST00000511764
ENST00000514697
ENST00000505457
ENST00000514410
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004652 polynucleotide adenylyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0043221 SMC family protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006261 DNA-dependent DNA replication
GO:0006302 double-strand break repair
GO:0007062 sister chromatid cohesion
GO:0007076 mitotic chromosome condensation
GO:0042493 response to drug
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034575
View Gene Order
ENSBTAG00000003381
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.481542
RefSeq NM_001171805 NM_001171806 NM_006999 XM_005248234 XM_006714438
HUGO
OMIM
CCDS CCDS3871
HPRD 09239
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca