Version 5.4
| Homo sapiens Gene: CACNA2D4 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-11938.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | CACNA2D4 | ||||||
| Gene Name | calcium channel, voltage-dependent, alpha 2/delta subunit 4 | ||||||
| Synonyms | |||||||
| Species | Homo sapiens | ||||||
| Ensembl Gene | ENSG00000151062 | ||||||
| Encoded Proteins |
calcium channel, voltage-dependent, alpha 2/delta subunit 4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 12:1791957-1918836 | ||||||
| Strand | Reverse strand | ||||||
| Band | p13.33 | ||||||
| Transcripts | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
MAPK signaling pathway pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
Hypertrophic cardiomyopathy (HCM) pathway
Cardiac muscle contraction pathway
Dilated cardiomyopathy pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | Q7Z3S7 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 93589 | ||||||
| UniGene | Hs.13768 | ||||||
| RefSeq | NM_172364 | ||||||
| HUGO | HGNC:20202 | ||||||
| OMIM | 608171 | ||||||
| CCDS | CCDS44785 | ||||||
| HPRD | 12182 | ||||||
| IMGT | |||||||
| EMBL | AC005342 AC005343 AF516695 BC048288 BX537436 BX537437 | ||||||
| GenPept | AAH48288 AAN06672 CAD97678 CAD97679 | ||||||
| RNA Seq Atlas | 93589 | ||||||