Homo sapiens Gene: ISCA2
Summary
InnateDB Gene IDBG-12166.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ISCA2
Gene Name iron-sulfur cluster assembly 2 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165898
Encoded Proteins
iron-sulfur cluster assembly 2 homolog (S. cerevisiae)
iron-sulfur cluster assembly 2 homolog (S. cerevisiae)
iron-sulfur cluster assembly 2 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. The encoded protein appears to be involved in the maturation of mitochondrial iron-sulfur proteins. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:74493720-74497106
Strand Forward strand
Band q24.3
Transcripts
ENST00000298818 ENSP00000298818
ENST00000556816 ENSP00000452007
ENST00000554924 ENSP00000450523
ENST00000555139
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0016226 iron-sulfur cluster assembly
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q86U28
TrEMBL G3V291 J3QSS7
UniProt Splice Variant
Entrez Gene 122961
UniGene Hs.721034
RefSeq NM_001272007 NM_194279
HUGO HGNC:19857
OMIM 615317
CCDS CCDS32122 CCDS61504
HPRD
IMGT
EMBL AC005479 AK290728 BC015771 BC032893 BX248252 CH471061
GenPept AAH15771 AAH32893 BAF83417 CAD62580 EAW81180
RNA Seq Atlas 122961