InnateDB Protein
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IDBP-583239.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ISCA2
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Protein Name
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iron-sulfur cluster assembly 2 homolog (S. cerevisiae)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000452007
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InnateDB Gene
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IDBG-12166 (ISCA2)
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Protein Structure
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Function |
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly. {ECO:0000269PubMed:22323289}.
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Subcellular Localization |
Mitochondrion {ECO:0000269PubMed:22323289}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000361
FeS cluster biogenesis
IPR016092
FeS cluster insertion protein
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PFAM |
PF01521
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q86U28
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PhosphoSite |
PhosphoSite-Q86U28
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
122961
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UniGene |
Hs.721034
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RefSeq |
NP_919255
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HUGO |
HGNC:19857
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OMIM |
615317
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CCDS |
CCDS32122
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HPRD |
17090
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IMGT |
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EMBL |
AC005479
AK290728
BC015771
BC032893
BX248252
CH471061
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GenPept |
AAH15771
AAH32893
BAF83417
CAD62580
EAW81180
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