Version 5.4
Homo sapiens Gene: N6AMT1
Summary
InnateDB Gene IDBG-1238.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol N6AMT1
Gene Name N-6 adenine-specific DNA methyltransferase 1 (putative)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000156239
Encoded Proteins
IDBP-1240
N-6 adenine-specific DNA methyltransferase 1 (putative)
IDBP-1242
N-6 adenine-specific DNA methyltransferase 1 (putative)
IDBP-602804
N-6 adenine-specific DNA methyltransferase 1 (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes protein methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:28872191-28885371
Strand Reverse strand
Band q21.3
Transcripts
ENST00000303775 ENSP00000303584
ENST00000351429 ENSP00000286764
ENST00000460212 ENSP00000436490
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008276 protein methyltransferase activity
Biological Process
GO:0006479 protein methylation
GO:0030307 positive regulation of cell growth
Cellular Component
GO:0005737 cytoplasm
GO:0043234 protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044442
View Gene Order
ENSBTAG00000001412
Not yet available
Cross-References
SwissProt Q9Y5N5
TrEMBL B2RA97
UniProt Splice Variant
Entrez Gene 29104
UniGene
RefSeq NM_013240 NM_182749
HUGO HGNC:16021
OMIM 614553
CCDS CCDS33525 CCDS33526
HPRD
IMGT
EMBL AF139682 AF227510 AK314100 AL163248 BC011554 CH471079
GenPept AAD38520 AAH11554 BAG36794 CAB90428 EAX09939 EAX09940 EAX09941
RNA Seq Atlas 29104

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca