Version 5.4
Mus musculus Gene: Mtpap
Summary
InnateDB Gene IDBG-127813.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtpap
Gene Name mitochondrial poly(A) polymerase
Synonyms 0610027A18Rik; AW551379; Papd1
Species Mus musculus
Ensembl Gene ENSMUSG00000024234
Encoded Proteins
IDBP-127815
mitochondrial poly(A) polymerase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107951:
The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3' poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.[provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:4375592-4397330
Strand Forward strand
Band A1
Transcripts
ENSMUST00000025077 ENSMUSP00000025077
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0002134 UTP binding
GO:0003723 RNA binding
GO:0004652 polynucleotide adenylyltransferase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0030145 manganese ion binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006378 mRNA polyadenylation
GO:0071044 histone mRNA catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000107951
View Gene Order
ENSBTAG00000004387
Not yet available
Cross-References
SwissProt Q9D0D3
TrEMBL
UniProt Splice Variant
Entrez Gene 67440
UniGene Mm.417307
RefSeq NM_026157 XM_006526182 XM_006526183 XM_006526184
OMIM
CCDS CCDS37718
HPRD
IMGT
MGI ID MGI:1914690
MGI Symbol Mtpap
EMBL AK011546 AK076565 AK135537 BC057643
GenPept AAH57643 BAB27689 BAC36396 BAE22572
RNA Seq Atlas 67440

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca