Mus musculus Gene: Mrpl21
Summary
InnateDB Gene IDBG-128171.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrpl21
Gene Name mitochondrial ribosomal protein L21
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000024829
Encoded Proteins
mitochondrial ribosomal protein L21
mitochondrial ribosomal protein L21
mitochondrial ribosomal protein L21
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197345:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:3282901-3292837
Strand Forward strand
Band A
Transcripts
ENSMUST00000025745 ENSMUSP00000025745
ENSMUST00000025743 ENSMUSP00000025743
ENSMUST00000139844
ENSMUST00000155870
ENSMUST00000141610 ENSMUSP00000120330
ENSMUST00000154785
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006412 translation
GO:0008150 biological_process
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005840 ribosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Mitochondrial translation pathway
Organelle biogenesis and maintenance pathway
Mitochondrial translation elongation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
KEGG
Ribosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.426899 Mm.443412 Mm.74084
RefSeq NM_172252 XM_006531777
OMIM
CCDS CCDS29394
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas