InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ndufa4

Summary

InnateDB Gene

IDBG-128495.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufa4

Gene Name

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4

Synonyms

MLRQ

Species

Mus musculus

Ensembl Gene

ENSMUSG00000029632

Encoded Proteins

IDBP-128497

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189043:
The protein encoded by this gene belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:11900373-11907446

Strand

Reverse strand

Band

Transcripts

ENSMUST00000031637

ENSMUSP00000031637

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004129	cytochrome-c oxidase activity
GO:0032403	protein complex binding

Biological Process

GO:0055114	oxidation-reduction process
GO:1902600	hydrogen ion transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005747	mitochondrial respiratory chain complex I
GO:0005751	mitochondrial respiratory chain complex IV
GO:0070062	extracellular vesicular exosome