Version 5.4
| Mus musculus Gene: Nsmaf | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-128647.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Nsmaf | ||||||||
| Gene Name | neutral sphingomyelinase (N-SMase) activation associated factor | ||||||||
| Synonyms | AA959567; C630007J05; Fan | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000028245 | ||||||||
| Encoded Proteins |
neutral sphingomyelinase (N-SMase) activation associated factor
neutral sphingomyelinase (N-SMase) activation associated factor
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000035681:
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 4:6396207-6454271 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | A1 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
TNFalpha pathway
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| REACTOME | |||||||||
| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
TNF receptor signaling pathway
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Mm.3059 | ||||||||
| RefSeq | NM_010945 XM_006537662 XM_006537663 XM_006537664 XM_006537665 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS17952 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | |||||||||
| MGI Symbol | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||