Version 5.4
| Mus musculus Protein: Nsmaf | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-128649.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Nsmaf | ||||||||
| Protein Name | neutral sphingomyelinase (N-SMase) activation associated factor | ||||||||
| Synonyms | AA959567; C630007J05; Fan; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000029910 | ||||||||
| InnateDB Gene | IDBG-128647 (Nsmaf) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N- smase activation domain of TNF-R55. May regulate ceramide production by N-SMASE. | ||||||||
| Subcellular Localization | |||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1341864 | ||||||||
| InterPro |
IPR000409
BEACH domain IPR001680 WD40 repeat IPR004182 GRAM domain IPR017986 WD40-repeat-containing domain |
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| PFAM |
PF02138
PF00400 PF02893 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM01026
SM00320 SM00568 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | O35242 | ||||||||
| PhosphoSite | PhosphoSite-O35242 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 18201 | ||||||||
| UniGene | Mm.3059 | ||||||||
| RefSeq | NP_035075 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Nsmaf | ||||||||
| OMIM | |||||||||
| CCDS | CCDS17952 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF013632 AL772306 BC145961 BC145963 BX510318 CH466538 | ||||||||
| GenPept | AAB65394 AAI45962 AAI45964 CAM20130 CAM27232 EDL05686 | ||||||||