Version 5.4
Mus musculus Gene: Klf6
Summary
InnateDB Gene IDBG-128907.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klf6
Gene Name Kruppel-like factor 6
Synonyms AI448727; BCD1; C86813; Copeb; CPBP; FM2; FM6; Ierepo1; Ierepo3; R75280; Zf9
Species Mus musculus
Ensembl Gene ENSMUSG00000000078
Encoded Proteins
IDBP-128909
Kruppel-like factor 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000067082:
This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:5861489-5870393
Strand Forward strand
Band A1
Transcripts
ENSMUST00000000080 ENSMUSP00000000080
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0019221 cytokine-mediated signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000067082
View Gene Order
ENSBTAG00000015188
Not yet available
Cross-References
SwissProt O08584
TrEMBL Q3U9J1 Q8BPQ2
UniProt Splice Variant
Entrez Gene 23849
UniGene Mm.275036 Mm.402344 Mm.465611
RefSeq NM_011803
OMIM
CCDS CCDS26229
HPRD
IMGT
MGI ID MGI:1346318
MGI Symbol Klf6
EMBL AC158535 AF072403 AK053584 AK144137 AK146615 AK151769 AK159420 AY027436 CH466588
GenPept AAC99478 AAK11733 BAC35438 BAE25722 BAE27304 BAE30675 BAE35068 EDL32266
RNA Seq Atlas 23849

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca