Version 5.4
Mus musculus Gene: Rbm14
Summary
InnateDB Gene IDBG-129915.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rbm14
Gene Name RNA binding motif protein 14
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000006456
Encoded Proteins
IDBP-129917
RNA binding motif protein 14
IDBP-253146
RNA binding motif protein 14
IDBP-704474
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000239306:
This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:4800569-4811634
Strand Reverse strand
Band A
Transcripts
ENSMUST00000006625 ENSMUSP00000006625
ENSMUST00000113793 ENSMUSP00000109424
ENSMUST00000180008 ENSMUSP00000137466
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 77 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 77 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0016575 histone deacetylation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000239306
View Gene Order
ENSBTAG00000001225
Not yet available
Cross-References
SwissProt
TrEMBL J3QPT3
UniProt Splice Variant
Entrez Gene 56275
UniGene Mm.276338 Mm.487245
RefSeq NM_019869 XM_006531799
OMIM
CCDS CCDS29437
HPRD
IMGT
MGI ID MGI:1929092
MGI Symbol Rbm14
EMBL AC141437
GenPept
RNA Seq Atlas 56275

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca