Version 5.4
Mus musculus Gene: Actn3
Summary
InnateDB Gene IDBG-130128.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Actn3
Gene Name actinin alpha 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000006457
Encoded Proteins
IDBP-130130
actinin alpha 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:4861223-4877909
Strand Reverse strand
Band A
Transcripts
ENSMUST00000006626 ENSMUSP00000006626
ENSMUST00000138811
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0030674 protein binding, bridging
GO:0042803 protein homodimerization activity
GO:0051015 actin filament binding
Biological Process
GO:0006936 muscle contraction
Cellular Component
GO:0005865 striated muscle thin filament
GO:0030017 sarcomere
GO:0030018 Z disc
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04530
Tight junction pathway
mmu04810
Regulation of actin cytoskeleton pathway
mmu04520
Adherens junction pathway
mmu04670
Leukocyte transendothelial migration pathway
mmu04510
Focal adhesion pathway
mmu05322
Systemic lupus erythematosus pathway
mmu05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
mmu05146
Amoebiasis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.5316
RefSeq NM_013456
OMIM
CCDS CCDS29441
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca