InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Vip

Summary

InnateDB Gene

IDBG-130461.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vip

Gene Name

vasoactive intestinal polypeptide

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000019772

Encoded Proteins

IDBP-130463

vasoactive intestinal polypeptide

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146469:
The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:5639218-5647614

Strand

Forward strand

Band

Transcripts

ENSMUST00000019906

ENSMUSP00000019906

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005179	hormone activity
GO:0005515	protein binding

Biological Process

GO:0001938	positive regulation of endothelial cell proliferation
GO:0007611	learning or memory
GO:0009966	regulation of signal transduction
GO:0010579	positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0032880	regulation of protein localization
GO:0043066	negative regulation of apoptotic process
GO:0043267	negative regulation of potassium ion transport
GO:0045732	positive regulation of protein catabolic process
GO:0045909	positive regulation of vasodilation
GO:0048662	negative regulation of smooth muscle cell proliferation
GO:0051930	regulation of sensory perception of pain
GO:0060406	positive regulation of penile erection