Version 5.4
Mus musculus Gene: Slc29a2
Summary
InnateDB Gene IDBG-130553.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc29a2
Gene Name solute carrier family 29 (nucleoside transporters), member 2
Synonyms Der12; Ent2; Hnp36
Species Mus musculus
Ensembl Gene ENSMUSG00000024891
Encoded Proteins
IDBP-130555
solute carrier family 29 (nucleoside transporters), member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174669:
The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:5024006-5031971
Strand Forward strand
Band A
Transcripts
ENSMUST00000025826 ENSMUSP00000025826
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005337 nucleoside transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0015858 nucleoside transport
GO:1901642 nucleoside transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000174669
View Gene Order
ENSBTAG00000012024
Not yet available
Pathways
NETPATH
REACTOME
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_232951
Transport of vitamins, nucleosides, and related molecules pathway
REACT_247934
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1206
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q61672
TrEMBL
UniProt Splice Variant
Entrez Gene 13340
UniGene Mm.4930
RefSeq NM_007854 XM_006531663
OMIM
CCDS CCDS50354
HPRD
IMGT
MGI ID MGI:1345278
MGI Symbol Slc29a2
EMBL AF183397 BC048958 CH466612 X86682
GenPept AAF78477 AAH48958 CAA60381 EDL33088
RNA Seq Atlas 13340

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca