Version 5.4
Mus musculus Gene: Fam105b
Summary
InnateDB Gene IDBG-131479.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fam105b
Gene Name family with sequence similarity 105, member B
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000046034
Encoded Proteins
IDBP-131481
family with sequence similarity 105, member B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154124:
Gene Information
Type Protein coding
Genomic Location Chromosome 15:27605919-27630693
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000059662 ENSMUSP00000057893
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0002040 sprouting angiogenesis
GO:0006508 proteolysis
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0045087 innate immune response
GO:0050728 negative regulation of inflammatory response
GO:0060070 canonical Wnt signaling pathway
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:1990108 protein linear deubiquitination
Cellular Component
GO:0005737 cytoplasm
GO:0071797 LUBAC complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000154124
View Gene Order
ENSBTAG00000003186
Not yet available
Cross-References
SwissProt Q3UCV8
TrEMBL
UniProt Splice Variant
Entrez Gene 432940
UniGene Mm.309164
RefSeq NM_001013792
OMIM
CCDS CCDS49586
HPRD
IMGT
MGI ID MGI:3577015
MGI Symbol Otulin
EMBL AK134955 AK150371 BC028541 BC087945 GL456173
GenPept AAH28541 AAH87945 BAE22354 BAE29504
RNA Seq Atlas 432940

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca