Version 5.4
Homo sapiens Gene: FAM105B
Summary
InnateDB Gene IDBG-13090.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM105B
Gene Name family with sequence similarity 105, member B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154124
Encoded Proteins
IDBP-13092
family with sequence similarity 105, member B
IDBP-474324
family with sequence similarity 105, member B
IDBP-477597
family with sequence similarity 105, member B
IDBP-480865
family with sequence similarity 105, member B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:14664664-14699711
Strand Forward strand
Band p15.2
Transcripts
ENST00000284274 ENSP00000284274
ENST00000503023 ENSP00000427016
ENST00000507335
ENST00000514913 ENSP00000421928
ENST00000506417 ENSP00000424966
ENST00000508678
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0002040 sprouting angiogenesis
GO:0006508 proteolysis
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0045087 innate immune response
GO:0050728 negative regulation of inflammatory response
GO:0060070 canonical Wnt signaling pathway
GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:1990108 protein linear deubiquitination
Cellular Component
GO:0005737 cytoplasm
GO:0071797 LUBAC complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000046034
View Gene Order
ENSBTAG00000003186
Not yet available
Cross-References
SwissProt Q96BN8
TrEMBL D6RD57
UniProt Splice Variant
Entrez Gene 90268
UniGene Hs.406335 Hs.615055 Hs.630498
RefSeq NM_138348
HUGO HGNC:25118
OMIM 615712
CCDS CCDS43302
HPRD
IMGT
EMBL AC010491 AK092203 BC007706 BC015392 CH471102
GenPept AAH07706 AAH15392 BAC03828 EAX08038 EAX08039
RNA Seq Atlas 90268

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca