Version 5.4
Mus musculus Gene: Ptprg
Summary
InnateDB Gene IDBG-132153.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptprg
Gene Name protein tyrosine phosphatase, receptor type, G
Synonyms 5430405N12Rik; AW046354; AW549872; RPTPgamma
Species Mus musculus
Ensembl Gene ENSMUSG00000021745
Encoded Proteins
IDBP-132155
protein tyrosine phosphatase, receptor type, G
IDBP-401749
protein tyrosine phosphatase, receptor type, G
IDBP-535986
protein tyrosine phosphatase, receptor type, G
IDBP-541826
protein tyrosine phosphatase, receptor type, G
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144724:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:11553532-12242041
Strand Forward strand
Band A1
Transcripts
ENSMUST00000022264 ENSMUSP00000022264
ENSMUST00000119888 ENSMUSP00000113679
ENSMUST00000142917 ENSMUSP00000121268
ENSMUST00000148113
ENSMUST00000155727 ENSMUSP00000121427
ENSMUST00000134290
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0016791 phosphatase activity
GO:0042802 identical protein binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0007420 brain development
GO:0010977 negative regulation of neuron projection development
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000144724
View Gene Order
ENSBTAG00000021911
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.405384 Mm.431266 Mm.475030
RefSeq NM_008981 XM_006517957
OMIM
CCDS CCDS26816
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca