Version 5.4
Bos taurus Gene: BT.92027
Summary
InnateDB Gene IDBG-645168.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.92027
Gene Name receptor-type tyrosine-protein phosphatase gamma
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021911
Encoded Proteins
IDBP-697855
receptor-type tyrosine-protein phosphatase gamma
IDBP-697858
receptor-type tyrosine-protein phosphatase gamma
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144724:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:39175038-40360572
Strand Reverse strand
Band
Transcripts
ENSBTAT00000029213 ENSBTAP00000029213
ENSBTAT00000063448 ENSBTAP00000054347
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0042802 identical protein binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000144724
View Gene Order
ENSMUSG00000021745
View Gene Order
Cross-References
SwissProt
TrEMBL F1MFJ3
UniProt Splice Variant
Entrez Gene 540575
UniGene Bt.92027
RefSeq NM_001076228
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02054196 DAAA02054197 DAAA02054198 DAAA02054199 DAAA02054200 DAAA02054201 DAAA02054202 DAAA02054203 DAAA02054204 DAAA02054205 DAAA02054206 DAAA02054207 DAAA02054208
GenPept
RNA Seq Atlas 540575

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca