Version 5.4
Mus musculus Gene: Fhl5
Summary
InnateDB Gene IDBG-132466.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fhl5
Gene Name four and a half LIM domains 5
Synonyms 1700027G07Rik; Act
Species Mus musculus
Ensembl Gene ENSMUSG00000028259
Encoded Proteins
IDBP-132468
four and a half LIM domains 5
IDBP-265028
four and a half LIM domains 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112214:
The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:25199908-25242876
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000029922 ENSMUSP00000029922
ENSMUST00000108204 ENSMUSP00000103839
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112214
View Gene Order
ENSBTAG00000001803
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9WTX7
TrEMBL
UniProt Splice Variant
Entrez Gene 57756
UniGene Mm.87325
RefSeq XM_006538125 NM_021318
OMIM
CCDS CCDS18009
HPRD
IMGT
MGI ID MGI:1913192
MGI Symbol Fhl5
EMBL AF083394 AK006414 BC048473
GenPept AAD23916 AAH48473 BAB24576
RNA Seq Atlas 57756

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca