Version 5.4
Mus musculus Gene: Rit2
Summary
InnateDB Gene IDBG-132519.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rit2
Gene Name Ras-like without CAAX 2
Synonyms RIBA; Rin; Roc2
Species Mus musculus
Ensembl Gene ENSMUSG00000057455
Encoded Proteins
IDBP-132521
Ras-like without CAAX 2
IDBP-533766
Ras-like without CAAX 2
IDBP-537401
Ras-like without CAAX 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152214:
RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:30973489-31317290
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000082070 ENSMUSP00000080724
ENSMUST00000153060 ENSMUSP00000114323
ENSMUST00000153196
ENSMUST00000139924 ENSMUSP00000122938
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000152214
View Gene Order
Pathways
NETPATH
REACTOME
REACT_231290
Signalling to ERKs pathway
REACT_248921
Signalling by NGF pathway
REACT_237883
NGF signalling via TRKA from the plasma membrane pathway
REACT_188257
Signal Transduction pathway
REACT_252757
Signalling to p38 via RIT and RIN pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_12077
Signalling to p38 via RIT and RIN pathway
REACT_11061
Signalling by NGF pathway
REACT_111102
Signal Transduction pathway
REACT_12058
Signalling to ERKs pathway
REACT_12056
NGF signalling via TRKA from the plasma membrane pathway
KEGG
INOH
PID NCI
mapktrkpathway
Trk receptor signaling mediated by the MAPK pathway
trkrpathway
Neurotrophic factor-mediated Trk receptor signaling
Cross-References
SwissProt
TrEMBL F2Z432
UniProt Splice Variant
Entrez Gene 19762
UniGene Mm.446239
RefSeq NM_009065
OMIM
CCDS CCDS29108
HPRD
IMGT
MGI ID MGI:108054
MGI Symbol Rit2
EMBL AC102497 AC102597 AC158499 AC164011
GenPept
RNA Seq Atlas 19762

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca