Version 5.4
Mus musculus Gene: Tsga14
Summary
InnateDB Gene IDBG-133354.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tsga14
Gene Name testis specific gene A14
Synonyms 1700017E11Rik; 2810431D15Rik; AI449046; AI503610; Tsga14
Species Mus musculus
Ensembl Gene ENSMUSG00000029790
Encoded Proteins
IDBP-133356
testis specific gene A14
IDBP-250306
testis specific gene A14
IDBP-250308
testis specific gene A14
IDBP-789181
centrosomal protein 41
IDBP-532538
testis specific gene A14
IDBP-625481
testis specific gene A14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106477:
This gene encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain. In human retinal pigment epithelial cells the protein localized to centrioles and cilia. Mutations in this gene have been associated with Joubert Syndrome 15; an autosomal recessive ciliopathy and neurological disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30653457-30693749
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000031810 ENSMUSP00000031810
ENSMUST00000115131 ENSMUSP00000110784
ENSMUST00000115130 ENSMUSP00000110783
ENSMUST00000140211 ENSMUSP00000138696
ENSMUST00000132763
ENSMUST00000153107
ENSMUST00000146951
ENSMUST00000140252
ENSMUST00000133373 ENSMUSP00000116240
ENSMUST00000169422 ENSMUSP00000128707
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0018095 protein polyglutamylation
GO:0042384 cilium assembly
Cellular Component
GO:0005813 centrosome
GO:0005814 centriole
GO:0005929 cilium
GO:0016020 membrane
GO:0036064 ciliary basal body
GO:0072372 primary cilium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000106477
View Gene Order
ENSBTAG00000007413
Not yet available
Pathways
NETPATH
REACTOME
REACT_245720
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_240530
G2/M Transition pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_243078
Loss of Nlp from mitotic centrosomes pathway
REACT_188804
Cell Cycle pathway
REACT_246508
Mitotic G2-G2/M phases pathway
REACT_244487
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_196635
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_253753
Centrosome maturation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160315
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_15364
Loss of Nlp from mitotic centrosomes pathway
REACT_15451
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_115566
Cell Cycle pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
REACT_223914
G2/M Transition pathway
REACT_215505
Cell Cycle, Mitotic pathway
REACT_205006
Loss of Nlp from mitotic centrosomes pathway
REACT_217933
Mitotic G2-G2/M phases pathway
REACT_214934
Cell Cycle pathway
REACT_214350
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_224118
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_215812
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_210400
Centrosome maturation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.419530 Mm.65389
RefSeq NM_031998 XM_006505207 XM_006505208 XM_006505210 XM_006505211 XM_006505212 XM_006505213
OMIM
CCDS CCDS19978
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca