InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tsga14

Summary

InnateDB Protein

IDBP-250308.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tsga14

Protein Name

testis specific gene A14

Synonyms

1700017E11Rik; 2810431D15Rik; AI449046; AI503610; Tsga14;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110783

InnateDB Gene

IDBG-133354 (Tsga14)

Protein Structure

UniProt Annotation

Function

Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium. {ECO:0000269PubMed:22246503}.

Subcellular Localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cell projection, cilium {ECO:0000269PubMed:22246503}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269PubMed:22246503}. Note=Localizes mainly to the cilium basal body and in primary cilia.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0015031	protein transport
GO:0018095	protein polyglutamylation
GO:0042384	cilium assembly

Cellular Component

GO:0005814	centriole
GO:0005929	cilium
GO:0036064	ciliary basal body
GO:0072372	primary cilium

Protein Structure and Domains

PDB ID

MGI:1891414

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99NF3

PhosphoSite

PhosphoSite-Q99NF3

TrEMBL

UniProt Splice Variant

Entrez Gene

83922

UniGene

Mm.65389

RefSeq

MGI ID

MGI Symbol

Cep41

OMIM

CCDS

HPRD

IMGT

EMBL

AC155656 AJ278891 AK019270 AK132495 AK161461 AK170213 BC031892 CH466533

GenPept

AAH31892 BAC25586 BAE21202 BAE36410 BAE41640 CAC33579 EDL13733