Version 5.4
Mus musculus Gene: Hspa14
Summary
InnateDB Gene IDBG-133420.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hspa14
Gene Name heat shock protein 14
Synonyms 70kDa; Hsp70-4; HSP70L1; hsr.1; NST-1
Species Mus musculus
Ensembl Gene ENSMUSG00000051396
Encoded Proteins
IDBP-133422
heat shock protein 14
IDBP-538150
heat shock protein 14
IDBP-539866
heat shock protein 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 21730052
Hspa14 binds directly to Tlr4 on dendritic cell surfaces and induces a robust Th1 response via the MAPK and NFkB signalling pathways.
InnateDB Annotation from Orthologs
Summary
PMID 21730052
[Homo sapiens] HSPA14 binds directly to TLR4 on dendritic cell surfaces and induces a robust Th1 response via the MAPK and NFkB signalling pathways.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187522:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:3488850-3512814
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000027961 ENSMUSP00000027961
ENSMUST00000129505
ENSMUST00000156008
ENSMUST00000139485
ENSMUST00000135157
ENSMUST00000124331 ENSMUSP00000119850
ENSMUST00000140494 ENSMUSP00000120385
ENSMUST00000148167
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000902 cell morphogenesis
GO:0008150 biological_process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000187522
View Gene Order
ENSBTAG00000016451
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.416061
RefSeq NM_015765
OMIM
CCDS CCDS15653
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca