InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Maob

Summary

InnateDB Gene

IDBG-133631.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Maob

Gene Name

monoamine oxidase B

Synonyms

6330414K01Rik; MAO-B

Species

Mus musculus

Ensembl Gene

ENSMUSG00000040147

Encoded Proteins

IDBP-133633

monoamine oxidase B

IDBP-622888

monoamine oxidase B

IDBP-622889

monoamine oxidase B

IDBP-622890

monoamine oxidase B

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000069535:
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:16709282-16817366

Strand

Reverse strand

Band

A1.2

Transcripts

ENSMUST00000040820	ENSMUSP00000040550
ENSMUST00000168613	ENSMUSP00000127235
ENSMUST00000163344	ENSMUSP00000131743
ENSMUST00000173143	ENSMUSP00000134555

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016491	oxidoreductase activity
GO:0042803	protein homodimerization activity
GO:0050660	flavin adenine dinucleotide binding

Biological Process

GO:0009636	response to toxic substance
GO:0010044	response to aluminum ion
GO:0010269	response to selenium ion
GO:0014063	negative regulation of serotonin secretion
GO:0021762	substantia nigra development
GO:0032496	response to lipopolysaccharide
GO:0042493	response to drug
GO:0045471	response to ethanol
GO:0045964	positive regulation of dopamine metabolic process
GO:0048545	response to steroid hormone
GO:0051412	response to corticosterone
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0005743	mitochondrial inner membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome