Version 5.4
Mus musculus Gene: Agtr1b
Summary
InnateDB Gene IDBG-133637.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Agtr1b
Gene Name angiotensin II receptor, type 1b
Synonyms Agtr-1b; Angtr-1b; AT1B; AT2R1B
Species Mus musculus
Ensembl Gene ENSMUSG00000054988
Encoded Proteins
IDBP-133639
angiotensin II receptor, type 1b
IDBP-627829
angiotensin II receptor, type 1b
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:20314473-20367177
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000068316 ENSMUSP00000068298
ENSMUST00000163776 ENSMUSP00000128724
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001596 angiotensin type I receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0004945 angiotensin type II receptor activity
GO:0017046 peptide hormone binding
GO:0043621 protein self-association
Biological Process
GO:0001568 blood vessel development
GO:0001666 response to hypoxia
GO:0001822 kidney development
GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0006954 inflammatory response
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007584 response to nutrient
GO:0019229 regulation of vasoconstriction
GO:0035902 response to immobilization stress
GO:0042493 response to drug
GO:0042756 drinking behavior
GO:0043627 response to estrogen
GO:0071549 cellular response to dexamethasone stimulus
GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis
Cellular Component
GO:0012506 vesicle membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0031983 vesicle lumen
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_188573
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_207651
G alpha (q) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04614
Renin-angiotensin system pathway
mmu04020
Calcium signaling pathway pathway
mmu04080
Neuroactive ligand-receptor interaction pathway
mmu04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.134863
RefSeq NM_175086
OMIM
CCDS CCDS17264
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca