Mus musculus Gene: Prpf18
Summary
InnateDB Gene IDBG-133771.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prpf18
Gene Name PRP18 pre-mRNA processing factor 18 homolog (yeast)
Synonyms 2810441A10Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000039449
Encoded Proteins
PRP18 pre-mRNA processing factor 18 homolog (yeast)
PRP18 pre-mRNA processing factor 18 homolog (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165630:
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:4622058-4652113
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000035721 ENSMUSP00000041428
ENSMUST00000153881
ENSMUST00000152362 ENSMUSP00000116495
ENSMUST00000140818
ENSMUST00000144650
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0019870 potassium channel inhibitor activity
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005575 cellular_component
GO:0005681 spliceosomal complex
GO:0016607 nuclear speck
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Spliceosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.38529
RefSeq NM_026045 XM_006497530
OMIM
CCDS CCDS15657
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas