Version 5.4
| Mus musculus Gene: Sesn3 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-134331.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Sesn3 | ||||||||
| Gene Name | sestrin 3 | ||||||||
| Synonyms | 5630400E15Rik; BC003348; SEST3 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000032009 | ||||||||
| Encoded Proteins |
sestrin 3
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149212:
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 9:14276301-14326138 | ||||||||
| Strand | Forward strand | ||||||||
| Band | A1 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
p53 signaling pathway pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
p53 signaling pathway pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9CYP7 | ||||||||
| TrEMBL | A2RSF4 Q8CAN4 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 75747 | ||||||||
| UniGene | |||||||||
| RefSeq | NM_030261 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS22820 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1922997 | ||||||||
| MGI Symbol | Sesn3 | ||||||||
| EMBL | AK017464 AK038408 AK155398 BC132086 BC138690 CH466522 | ||||||||
| GenPept | AAI32087 AAI38691 BAB30755 BAC29988 BAE33242 EDL24990 | ||||||||
| RNA Seq Atlas | 75747 | ||||||||