Version 5.4
Mus musculus Gene: Slc9a7
Summary
InnateDB Gene IDBG-134340.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc9a7
Gene Name solute carrier family 9 (sodium/hydrogen exchanger), member 7
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037341
Encoded Proteins
IDBP-134342
solute carrier family 9 (sodium/hydrogen exchanger), member 7
IDBP-249740
solute carrier family 9 (sodium/hydrogen exchanger), member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000065923:
This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome X:20105755-20291807
Strand Reverse strand
Band A1.3
Transcripts
ENSMUST00000072451 ENSMUSP00000072274
ENSMUST00000115393 ENSMUSP00000111051
ENSMUST00000151845
ENSMUST00000130938
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015299 solute:proton antiporter activity
GO:0015385 sodium:proton antiporter activity
GO:0015386 potassium:hydrogen antiporter activity
Biological Process
GO:0006812 cation transport
GO:0006814 sodium ion transport
GO:0006885 regulation of pH
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005802 trans-Golgi network
GO:0016021 integral component of membrane
GO:0055038 recycling endosome membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000065923
View Gene Order
ENSBTAG00000003290
Not yet available
Pathways
NETPATH
REACTOME
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_259261
Sodium/Proton exchangers pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19314
Sodium/Proton exchangers pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8BLV3
TrEMBL
UniProt Splice Variant
Entrez Gene 236727
UniGene Mm.132983 Mm.419913
RefSeq NM_177353 XM_006527616
OMIM
CCDS CCDS40884
HPRD
IMGT
MGI ID MGI:2444530
MGI Symbol Slc9a7
EMBL AK041169 AL663098 BC058750
GenPept AAH58750 BAC30848 CAM18655 CAM18656
RNA Seq Atlas 236727

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca