Version 5.4
Mus musculus Protein: Slc9a7
Summary
InnateDB Protein IDBP-249740.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc9a7
Protein Name solute carrier family 9 (sodium/hydrogen exchanger), member 7
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000111051
InnateDB Gene IDBG-134340 (Slc9a7)
Protein Structure
UniProt Annotation
Function Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Recycling endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015299 solute:proton antiporter activity
GO:0015385 sodium:proton antiporter activity
GO:0015386 potassium:hydrogen antiporter activity
Biological Process
GO:0006812 cation transport
GO:0006814 sodium ion transport
GO:0006885 regulation of pH
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005802 trans-Golgi network
GO:0016021 integral component of membrane
GO:0055038 recycling endosome membrane
Protein Structure and Domains
PDB ID MGI:2444530
InterPro IPR002090 Na+/H+ exchanger, isoform 6 (NHE6)
IPR004709 Na+/H+ exchanger
IPR006153 Cation/H+ exchanger
PFAM PF00999
PRINTS PR01088
PR01084
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BLV3
PhosphoSite PhosphoSite-Q8BLV3
TrEMBL
UniProt Splice Variant
Entrez Gene 236727
UniGene Mm.419913
RefSeq
MGI ID
MGI Symbol Slc9a7
OMIM
CCDS
HPRD
IMGT
EMBL AK041169 AL663098 BC058750
GenPept AAH58750 BAC30848 CAM18655 CAM18656

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca