Version 5.4
Homo sapiens Gene: BASP1
Summary
InnateDB Gene IDBG-13455.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BASP1
Gene Name brain abundant, membrane attached signal protein 1
Synonyms CAP-23; CAP23; NAP-22; NAP22
Species Homo sapiens
Ensembl Gene ENSG00000176788
Encoded Proteins
IDBP-13457
brain abundant, membrane attached signal protein 1
IDBP-808584
brain abundant, membrane attached signal protein 1
IDBP-808590
brain abundant, membrane attached signal protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:17065598-17276843
Strand Forward strand
Band p15.1
Transcripts
ENST00000322611 ENSP00000319281
ENST00000606445 ENSP00000476090
ENST00000616743 ENSP00000482066
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0007356 thorax and anterior abdomen determination
GO:0008406 gonad development
GO:0021762 substantia nigra development
GO:0045892 negative regulation of transcription, DNA-templated
GO:0060231 mesenchymal to epithelial transition
GO:0060421 positive regulation of heart growth
GO:0060539 diaphragm development
GO:0072075 metanephric mesenchyme development
GO:0072112 glomerular visceral epithelial cell differentiation
GO:2001076 positive regulation of metanephric ureteric bud development
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0008180 COP9 signalosome
GO:0016607 nuclear speck
GO:0030054 cell junction
GO:0030426 growth cone
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000045763
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.201641
RefSeq NM_001271606 NM_006317
HUGO
OMIM
CCDS CCDS3888
HPRD 08389
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca