InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BASP1

Summary

InnateDB Protein

IDBP-13457.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BASP1

Protein Name

brain abundant, membrane attached signal protein 1

Synonyms

CAP-23; CAP23; NAP-22; NAP22;

Species

Homo sapiens

Ensembl Protein

ENSP00000319281

InnateDB Gene

IDBG-13455 (BASP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cell membrane; Lipid-anchor. Cell projection, growth cone. Note=Associated with the membranes of growth cones that form the tips of elongating axons.

Disease Associations

Tissue Specificity

Brain.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003714	transcription corepressor activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0007356	thorax and anterior abdomen determination
GO:0008406	gonad development
GO:0021762	substantia nigra development
GO:0045892	negative regulation of transcription, DNA-templated
GO:0060231	mesenchymal to epithelial transition
GO:0060421	positive regulation of heart growth
GO:0060539	diaphragm development
GO:0072075	metanephric mesenchyme development
GO:0072112	glomerular visceral epithelial cell differentiation
GO:2001076	positive regulation of metanephric ureteric bud development

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0008180	COP9 signalosome
GO:0016607	nuclear speck
GO:0030054	cell junction
GO:0030426	growth cone
GO:0070062	extracellular vesicular exosome