Mus musculus Gene: Fbxo43
Summary
InnateDB Gene IDBG-134920.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo43
Gene Name F-box protein 43
Synonyms 4930533G20Rik; Emi2
Species Mus musculus
Ensembl Gene ENSMUSG00000048230
Encoded Proteins
F-box protein 43
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156509:
Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:36150060-36164884
Strand Reverse strand
Band B3.1
Transcripts
ENSMUST00000058643 ENSMUSP00000054125
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0007126 meiotic nuclear division
GO:0016567 protein ubiquitination
GO:0040020 regulation of meiosis
GO:0042177 negative regulation of protein catabolic process
GO:0045835 negative regulation of meiosis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Oocyte meiosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Oocyte meiosis pathway
INOH
PID NCI
Cross-References
SwissProt Q8CDI2
TrEMBL G3X9B2
UniProt Splice Variant
Entrez Gene 78803
UniGene Mm.26393 Mm.421923
RefSeq NM_001081253 XM_006520197
OMIM
CCDS CCDS37060
HPRD
IMGT
MGI ID MGI:1926053
MGI Symbol Fbxo43
EMBL AC121577 AK030012 BC026503 BC098484 CH466541
GenPept AAH26503 AAH98484 BAC26733 EDL08829
RNA Seq Atlas 78803