Version 5.4
Mus musculus Gene: Eif5a2
Summary
InnateDB Gene IDBG-135186.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif5a2
Gene Name eukaryotic translation initiation factor 5A2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000050192
Encoded Proteins
IDBP-135188
eukaryotic translation initiation factor 5A2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163577:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:28781311-28798846
Strand Forward strand
Band A3
Transcripts
ENSMUST00000060500 ENSMUSP00000050289
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0005515 protein binding
GO:0043022 ribosome binding
Biological Process
GO:0006452 translational frameshifting
GO:0008284 positive regulation of cell proliferation
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
GO:0015031 protein transport
GO:0045901 positive regulation of translational elongation
GO:0045905 positive regulation of translational termination
GO:0051028 mRNA transport
Cellular Component
GO:0005643 nuclear pore
GO:0005789 endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163577
View Gene Order
ENSBTAG00000010550
Not yet available
Pathways
NETPATH
REACTOME
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_229541
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
REACT_203391
Hypusine synthesis from eIF5A-lysine pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_12469
Hypusine synthesis from eIF5A-lysine pathway
REACT_22161
Post-translational protein modification pathway
REACT_1069
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8BGY2
TrEMBL Q8CH67 Q8VHU9
UniProt Splice Variant
Entrez Gene 208691
UniGene Mm.193670 Mm.401537 Mm.414577 Mm.455477
RefSeq NM_177586
OMIM
CCDS CCDS17277
HPRD
IMGT
MGI ID MGI:1933735
MGI Symbol Eif5a2
EMBL AF377869 AF379605 AK052412 AK082214 AY205262 AY205263 AY205264 AY205265 BC106843 BC106844
GenPept AAI06844 AAI06845 AAL40919 AAO17899 AAO18680 AAO18681 AAO18682 AAO18683 BAC34978 BAC38441
RNA Seq Atlas 208691

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca