Version 5.4
Homo sapiens Gene: EIF5A2
Summary
InnateDB Gene IDBG-64663.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF5A2
Gene Name eukaryotic translation initiation factor 5A2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000163577
Encoded Proteins
IDBP-64665
eukaryotic translation initiation factor 5A2
IDBP-475785
eukaryotic translation initiation factor 5A2
IDBP-482357
eukaryotic translation initiation factor 5A2
IDBP-474052
eukaryotic translation initiation factor 5A2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:170888415-170908693
Strand Reverse strand
Band q26.2
Transcripts
ENST00000295822 ENSP00000295822
ENST00000460117
ENST00000487522 ENSP00000418305
ENST00000474096 ENSP00000418370
ENST00000474417 ENSP00000417133
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0005515 protein binding
GO:0043022 ribosome binding
Biological Process
GO:0006452 translational frameshifting
GO:0007283 spermatogenesis
GO:0008284 positive regulation of cell proliferation
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
GO:0010509 polyamine homeostasis
GO:0015031 protein transport
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0045901 positive regulation of translational elongation
GO:0045905 positive regulation of translational termination
GO:0051028 mRNA transport
Cellular Component
GO:0005643 nuclear pore
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000050192
View Gene Order
ENSBTAG00000010550
Not yet available
Pathways
NETPATH
REACTOME
REACT_12469
Hypusine synthesis from eIF5A-lysine pathway
REACT_22161
Post-translational protein modification pathway
REACT_1069
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.164144
RefSeq NM_020390
HUGO
OMIM
CCDS CCDS3214
HPRD 10426
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca