Version 5.4
Mus musculus Gene: Stra8
Summary
InnateDB Gene IDBG-135192.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stra8
Gene Name stimulated by retinoic acid gene 8
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029848
Encoded Proteins
IDBP-135194
stimulated by retinoic acid gene 8
IDBP-250604
stimulated by retinoic acid gene 8
IDBP-250606
stimulated by retinoic acid gene 8
IDBP-788858
stimulated by retinoic acid gene 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146857:
This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:34920163-34939344
Strand Forward strand
Band B1
Transcripts
ENSMUST00000031876 ENSMUSP00000031876
ENSMUST00000114999 ENSMUSP00000110651
ENSMUST00000114997 ENSMUSP00000110649
ENSMUST00000185102 ENSMUSP00000139136
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0001541 ovarian follicle development
GO:0006260 DNA replication
GO:0007066 female meiosis sister chromatid cohesion
GO:0007129 synapsis
GO:0007131 reciprocal meiotic recombination
GO:0007283 spermatogenesis
GO:0009566 fertilization
GO:0010032 meiotic chromosome condensation
GO:0033315 meiotic DNA replication checkpoint
GO:0042138 meiotic DNA double-strand break formation
GO:0046620 regulation of organ growth
GO:0048599 oocyte development
GO:0071300 cellular response to retinoic acid
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000146857
View Gene Order
ENSBTAG00000001346
Not yet available
Cross-References
SwissProt
TrEMBL V9GXG4
UniProt Splice Variant
Entrez Gene 20899
UniGene
RefSeq NM_009292
OMIM
CCDS CCDS39458
HPRD
IMGT
MGI ID MGI:107917
MGI Symbol Stra8
EMBL AC153869
GenPept
RNA Seq Atlas 20899

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca