InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Stra8

Summary

InnateDB Protein

IDBP-250604.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Stra8

Protein Name

stimulated by retinoic acid gene 8

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110651

InnateDB Gene

IDBG-135192 (Stra8)

Protein Structure

UniProt Annotation

Function

Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase. {ECO:0000269PubMed:16461896, ECO:0000269PubMed:17115059}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:8896602}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0046983	protein dimerization activity

Biological Process

GO:0001541	ovarian follicle development
GO:0006260	DNA replication
GO:0007066	female meiosis sister chromatid cohesion
GO:0007129	synapsis
GO:0007131	reciprocal meiotic recombination
GO:0007283	spermatogenesis
GO:0009566	fertilization
GO:0010032	meiotic chromosome condensation
GO:0033315	meiotic DNA replication checkpoint
GO:0042138	meiotic DNA double-strand break formation
GO:0046620	regulation of organ growth
GO:0048599	oocyte development
GO:0071300	cellular response to retinoic acid