Mus musculus Gene: Atp4b
Summary
InnateDB Gene IDBG-135260.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atp4b
Gene Name ATPase, H+/K+ exchanging, beta polypeptide
Synonyms AV080843
Species Mus musculus
Ensembl Gene ENSMUSG00000031449
Encoded Proteins
ATPase, H+/K+ exchanging, beta polypeptide
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186009:
The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:13386209-13396778
Strand Reverse strand
Band A1.1
Transcripts
ENSMUST00000033826 ENSMUSP00000033826
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008900 hydrogen:potassium-exchanging ATPase activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006813 potassium ion transport
GO:0006814 sodium ion transport
GO:0007155 cell adhesion
GO:0010155 regulation of proton transport
GO:0010243 response to organonitrogen compound
GO:0032496 response to lipopolysaccharide
GO:0033577 protein glycosylation in endoplasmic reticulum
GO:0045851 pH reduction
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005890 sodium:potassium-exchanging ATPase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
KEGG
Oxidative phosphorylation pathway
Gastric acid secretion pathway
Collecting duct acid secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Ion transport by P-type ATPases pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
KEGG
Oxidative phosphorylation pathway
Gastric acid secretion pathway
Collecting duct acid secretion pathway
INOH
PID NCI
Cross-References
SwissProt P50992
TrEMBL Q0VBB6
UniProt Splice Variant
Entrez Gene 11945
UniGene Mm.154039
RefSeq NM_009724
OMIM
CCDS CCDS22111
HPRD
IMGT
MGI ID MGI:88114
MGI Symbol Atp4b
EMBL AK008180 AK009499 AK009832 AK009994 AK010003 AK010030 AK010049 BC120705 BC125292 CH466566 M64685 M64686 M64687 M64688 M80247 M80248 M80249 M80250 M80251
GenPept AAA37269 AAA37270 AAI20706 AAI25293 BAB25514 BAB26326 BAB26530 BAB26632 BAB26635 BAB26654 BAB26665 EDL22143
RNA Seq Atlas 11945