InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atp4b

Summary

InnateDB Protein

IDBP-135264.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp4b

Protein Name

ATPase, H+/K+ exchanging, beta polypeptide

Synonyms

AV080843;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033826

InnateDB Gene

IDBG-135260 (Atp4b)

Protein Structure

UniProt Annotation

Function

Required for stabilization and maturation of the catalytic proton pump alpha subunit and may also involved in cell adhesion and establishing epithelial cell polarity. {ECO:0000250}.

Subcellular Localization

Cell membrane; Single-pass type II membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008900	hydrogen:potassium-exchanging ATPase activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006813	potassium ion transport
GO:0006814	sodium ion transport
GO:0007155	cell adhesion
GO:0010155	regulation of proton transport
GO:0010243	response to organonitrogen compound
GO:0032496	response to lipopolysaccharide
GO:0033577	protein glycosylation in endoplasmic reticulum
GO:0045851	pH reduction
GO:1902600	hydrogen ion transmembrane transport