Version 5.4
Mus musculus Gene: Btn1a1
Summary
InnateDB Gene IDBG-135787.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Btn1a1
Gene Name butyrophilin, subfamily 1, member A1
Synonyms Btn
Species Mus musculus
Ensembl Gene ENSMUSG00000000706
Encoded Proteins
IDBP-135789
butyrophilin, subfamily 1, member A1
IDBP-260283
butyrophilin, subfamily 1, member A1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124557:
Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:23456992-23465901
Strand Reverse strand
Band A3.1
Transcripts
ENSMUST00000041674 ENSMUSP00000041013
ENSMUST00000110434 ENSMUSP00000106064
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0031324 negative regulation of cellular metabolic process
GO:0046007 negative regulation of activated T cell proliferation
GO:0050710 negative regulation of cytokine secretion
Cellular Component
GO:0005615 extracellular space
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124557
View Gene Order
ENSBTAG00000010852
Not yet available
Cross-References
SwissProt
TrEMBL Q921X1 Q9D1U4
UniProt Splice Variant
Entrez Gene 12231
UniGene Mm.1420
RefSeq NM_013483 XM_006516535
OMIM
CCDS CCDS26339
HPRD
IMGT
MGI ID MGI:103118
MGI Symbol Btn1a1
EMBL AK021333 AL714025 BC009817 CH466561
GenPept AAH09817 BAB32377 EDL32570
RNA Seq Atlas 12231

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca