Version 5.4
Mus musculus Gene: Gfra3
Summary
InnateDB Gene IDBG-135800.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gfra3
Gene Name glial cell line derived neurotrophic factor family receptor alpha 3
Synonyms GFRalpha3; Y15110
Species Mus musculus
Ensembl Gene ENSMUSG00000024366
Encoded Proteins
IDBP-135802
glial cell line derived neurotrophic factor family receptor alpha 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146013:
The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:34689903-34720387
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000025224 ENSMUSP00000025224
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008046 axon guidance receptor activity
GO:0015026 coreceptor activity
Biological Process
GO:0001764 neuron migration
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007411 axon guidance
GO:0048485 sympathetic nervous system development
GO:0048666 neuron development
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0031225 anchored component of membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000146013
View Gene Order
ENSBTAG00000005288
Not yet available
Cross-References
SwissProt O35118
TrEMBL
UniProt Splice Variant
Entrez Gene 14587
UniGene Mm.16520
RefSeq NM_010280
OMIM
CCDS CCDS29133
HPRD
IMGT
MGI ID MGI:1201403
MGI Symbol Gfra3
EMBL AB008833 AF020305 AF036163 AF041842 AF051766 AK046542 BC066202
GenPept AAB70931 AAC23558 AAC24354 AAC24468 AAH66202 BAA23562 BAC32778
RNA Seq Atlas 14587

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca