Version 5.4
Homo sapiens Gene: GFRA3
Summary
InnateDB Gene IDBG-46879.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GFRA3
Gene Name GDNF family receptor alpha 3
Synonyms GDNFR3
Species Homo sapiens
Ensembl Gene ENSG00000146013
Encoded Proteins
IDBP-46881
GDNF family receptor alpha 3
IDBP-46883
GDNF family receptor alpha 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:138252379-138274671
Strand Reverse strand
Band q31.2
Transcripts
ENST00000378362 ENSP00000367613
ENST00000274721 ENSP00000274721
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0008046 axon guidance receptor activity
Biological Process
GO:0001764 neuron migration
GO:0007165 signal transduction
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0007422 peripheral nervous system development
GO:0048485 sympathetic nervous system development
GO:0048666 neuron development
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0019898 extrinsic component of membrane
GO:0031225 anchored component of membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024366
View Gene Order
ENSBTAG00000005288
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.58042
RefSeq NM_001496
HUGO
OMIM
CCDS CCDS4201
HPRD 10420
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca