Mus musculus Gene: Crisp4
Summary
InnateDB Gene IDBG-135823.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crisp4
Gene Name cysteine-rich secretory protein 4
Synonyms 9230112K08Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000025774
Encoded Proteins
cysteine-rich secretory protein 4
cysteine-rich secretory protein 4
cysteine-rich secretory protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124812:
Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:18115191-18145902
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000026876 ENSMUSP00000026876
ENSMUST00000115344 ENSMUSP00000111001
ENSMUST00000115340 ENSMUSP00000110997
ENSMUST00000130669
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005246 calcium channel regulator activity
Biological Process
GO:0007339 binding of sperm to zona pellucida
GO:0060046 regulation of acrosome reaction
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.319913
RefSeq NM_030033 XM_006495588 XM_006495589 XM_006495590
OMIM
CCDS CCDS14835
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas