Version 5.4
Bos taurus Gene: CRISP1
Summary
InnateDB Gene IDBG-632504.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CRISP1
Gene Name cysteine-rich secretory protein 1 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008085
Encoded Proteins
IDBP-684126
cysteine-rich secretory protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124812:
Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:22245233-22261583
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010633 ENSBTAP00000010633
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005246 calcium channel regulator activity
Biological Process
GO:0007339 binding of sperm to zona pellucida
GO:0060046 regulation of acrosome reaction
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000124812
View Gene Order
ENSMUSG00000025774
View Gene Order
Cross-References
SwissProt
TrEMBL E1BC47
UniProt Splice Variant
Entrez Gene 616774
UniGene Bt.112400
RefSeq NM_001206259
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02055215 DAAA02055216
GenPept
RNA Seq Atlas 616774

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca